Catalog/Weight Management/AOD-9604

AOD-9604

AOD-9604 (Anti-Obesity Drug 9604) is a peptide fragment corresponding to amino acids 176–191 of human growth hormone, modified with an N-terminal tyrosine. Unlike full-length hGH, …

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Purity98.8%
HPLC verified · MS confirmed
FormulaC₇₈H₁₂₃N₂₃O₂₃S₂
Mol. Weight1815.1 g/mol
Half-Life~30 minutes
FormLyophilized powder
CAS221231-10-3
CoA Included3rd-party testedFor Research Use Only

AOD-9604 (Anti-Obesity Drug 9604) is a peptide fragment corresponding to amino acids 176–191 of human growth hormone, modified with an N-terminal tyrosine. Unlike full-length hGH, it does not stimulate IGF-1 or affect glucose metabolism, making it a target for isolated fat metabolism research. Studies demonstrate stimulation of lipolysis and inhibition of lipogenesis via beta-3 adrenergic receptors.

Research Highlights

  • Stimulates beta-3 adrenergic receptor-mediated lipolysis in adipocytes
  • Inhibits lipogenesis without IGF-1 elevation or glucose interference
  • Demonstrated anti-obesity effects in diet-induced obesity murine models
  • No significant effect on blood glucose or insulin sensitivity at research doses

Key References

1
A fragment of the human growth hormone reduces body weightEat Weight Disord · 2001
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