Catalog/Performance/Hexarelin

Hexarelin

Hexarelin is a synthetic hexapeptide GHRP (His-D-2MeTrp-Ala-Trp-D-Phe-Lys-NH₂) and potent agonist of the GHSR receptor. It is one of the most studied growth hormone secretagogues…

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Purity99.0%
HPLC verified · MS confirmed
FormulaC₄₇H₅₈N₁₂O₆
Mol. Weight887.1 g/mol
Half-Life~1–2 hours
FormLyophilized powder
CAS140703-51-1
CoA Included3rd-party testedFor Research Use Only

Hexarelin is a synthetic hexapeptide GHRP (His-D-2MeTrp-Ala-Trp-D-Phe-Lys-NH₂) and potent agonist of the GHSR receptor. It is one of the most studied growth hormone secretagogues in the literature, with research investigating not only GH release but also direct cardiac protection via CD36 receptor binding, independent of GH axis activation. Cardioprotective effects in ischemia-reperfusion models are a key area of investigation.

Research Highlights

  • Most potent GHSR agonist among GHRPs; robust GH pulse amplitude elevation
  • Direct cardioprotection via CD36 scavenger receptor — independent of GH
  • Reduces infarct size and improves cardiac function post-ischemia in vivo
  • Synergistic GH release with GHRH analogues in pituitary studies

Key References

1
Hexarelin, a synthetic GHRP, protects the heart from ischemia-reperfusion injuryEndocrinology · 2002
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