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Catalog/Performance/Tesamorelin

Tesamorelin

Tesamorelin is a GHRH(1–44) analogue with a trans-3-hexenoic acid group conjugated to the N-terminal tyrosine to improve metabolic stability. Originally studied in the context of…

$577per kit · lyophilized
Qty
1
$577
≥98.5% (HPLC/MS)CoA on every orderFree shipping on kit orders
Purity98.5%
HPLC verified · MS confirmed
FormulaC₂₂₁H₃₆₆N₆₈O₆₇S
Mol. Weight5135.8 g/mol
Half-Life~38 minutes
FormLyophilized powder
CAS218949-48-5
CoA Included3rd-party testedFor Research Use Only

Tesamorelin is a GHRH(1–44) analogue with a trans-3-hexenoic acid group conjugated to the N-terminal tyrosine to improve metabolic stability. Originally studied in the context of HIV-associated lipodystrophy, it has been investigated for visceral adipose tissue reduction, IGF-1 elevation, and cognitive function in aging models. It is one of the best-characterized GHRH analogues in clinical research literature.

Research Highlights

  • Reduces visceral adipose tissue area in HIV-associated lipodystrophy and obesity models
  • Consistent IGF-1 elevation without supraphysiologic GH spiking
  • Cognitive improvement in MCI-associated aging models via IGF-1 signaling
  • Favorable lipid panel changes: reduced total cholesterol and triglycerides

Key References

1
Tesamorelin reduces visceral fat in HIV-infected patientsN Engl J Med · 2010