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Catalog/Nootropics/Semax

Semax

Semax is a synthetic heptapeptide based on the ACTH (4–7) fragment Met-Glu-His-Phe extended with Pro-Gly-Pro. Developed in the Soviet Union and studied extensively at the…

$433per kit · lyophilized
Qty
1
$433
≥99.1% (HPLC)CoA on every orderFree shipping on kit orders
Purity99.1%
HPLC verified · MS confirmed
FormulaC₃₇H₅₁N₉O₁₀S
Mol. Weight813.9 g/mol
Half-Life~2 minutes
FormLyophilized powder
CAS80714-61-0
CoA Included3rd-party testedFor Research Use Only

Semax is a synthetic heptapeptide based on the ACTH (4–7) fragment Met-Glu-His-Phe extended with Pro-Gly-Pro. Developed in the Soviet Union and studied extensively at the Institute of Molecular Genetics, it has been investigated for neuroprotective, nootropic, and anxiolytic properties. Research documents upregulation of BDNF, NGF, and VEGF, improved attention and working memory, and protection against ischemic neuronal damage.

Research Highlights

  • Upregulates BDNF and VEGF expression in cerebral cortex and hippocampus
  • Neuroprotective in stroke and ischemia-reperfusion rodent models
  • Enhances attention, learning rate, and spatial memory in test models
  • Modulates serotonin and dopamine systems via ACTH receptor pathways

Key References

1
Semax is an analog of the ACTH 4-10 peptide with long-lasting nootropic effectsPeptides · 2010